The House of the Dead is a rail shooter. Go through the four chapters with branching paths and kill all the zombies, avoid killing the humans, and rescue the girl. Shooting various special targets along the way or in a certain time period give the player temporary health and weapon upgrades. The Saturn version of the game contains two extra modes called Saturn Mode and Boss Mode. Saturn mode plays like the arcade game, but offers the player different characters to choose from. Character selection matters since they each have varying attributes such as their reload time and how much damage they can take before dying. The Boss Mode allows the player to fight one boss of their choosing or all of the game's four boss monsters consecutively.
| Boxed A | Factory Sealed Product |
| Boxed B | Product Boxed & Complete with Manual |
| Boxed C | Product Boxed without Manual |
| D | Loose Item |
